ACCOMPLISHMENTS BY FACULTY MEMBER

• BAHMAN ANVARI

  GRANTS	PUBLICATIONS	RECOGNITIONS AND ENGAGEMENTS
  Principal Investigator (Contact-PI), “Erythrocyte-derived particles for near infrared phototherapy of port wine stains,” National Institute of Arthritis and Musculoskeletal and Skin Diseases (2R01-AR068067-05A1), $2,045,601.	B. Anvari, C. De Angelis, S. Huang, N. Litchinitser, T. -C. Poon, G. Scalari, B. S. Richards, and M. Peccianti, “Frontiers in Photonics Spot Light,” Frontiers in Photonics, 3, 853456, 2022. J. T. Mac, R. Vankayala, C. -H. Lee, and B. Anvari, “Erythrocyte-derived nanoparticles with folate functionalization for near infrared pulsed laser-mediated photo-chemotherapy of tumors,” International Journal of Molecular Sciences, 23, 10296, doi: 10.3390/ilms231810295, 2022. T. Lu, C. -H. Lee, and B. Anvari, “Morphological characteristics, hemoglobin content, and membrane mechanical properties of red blood cell delivery systems,” ACS Applied Materials & Interfaces, 14, 18219-18232, 2022. J. C. Tang*, C. -H. Lee*, T. Lu, R. Vankayala, T. Hanley, C. Azubuogu, J. Li, M. Nair, W. Jia, and B. Anvari, “Membrane cholesterol enrichment of red blood cell-derived microparticles results in prolonged circulation,” ACS Applied Bio Materials, 5, 650-660, 2022 (*equally contributed)	Appointed as Editor-in-Chief, Biological and Bio- Materials Section, Biomolecules

   

• VASILEIOS CHRISTOPOULOS

  GRANTS	PUBLICATIONS	RECOGNITIONS AND ENGAGEMENTS
  2022-2027 RFA-NS-19-001: U01 BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain: Title: Sensory motor transformations in human cortex. Role: UCR Principal Investigator (Contact PI: Richard Andersen, Caltech) 2022-2025 RFA-NS-18-020: R01 BRAIN Initiative: New Technologies and Novel Approaches for Large-Scale Recording and Modulation in the Nervous System : Title: Minimally Invasive Ultrasonic Brain-Machine Interface. Role: UCR Principal Investigator (Contact PI: Richard Andersen, Caltech) 2/13 2022-2023 RFA-HD-20-004: NIH Center for Smart Use of Technologies to Assess Real-World Outcomes (C-STAR) - Pilot grant: Title: Detection and characterization of motor activity in behaving infants through the use of novel ultrasonic brain imaging technology. Role: Principal Investigator	Agyeman K, Lee DJ, Russin J, Kreydin EI, Choi W, AbediA , Edgerton VR, Liu C, Christopoulos VN Functional Ultrasound Imaging of the Human Spinal Cord, bioRxiv 2022.08.06.503044 – (Nature Communications. Under Review) ZhongS, Choi JW, Hashoush NG, Malekmohammadi M, Pouratian N, Christopoulos VN (2022) A neurocomputational model of action regula[1]tion predicts motor behavior in neurotypical individuals and patients with Parkinson’s disease PLoS Comput Biol (In press)	Hellman Fellowship

• KEVIN FREEDMAN

  GRANTS

  PUBLICATIONS

  NIH R21:  Single Molecule Protein Sequencing using Nanopores and Deep-UV Raman Spectroscopy

  YMNDY Bandara, N Farajpour, KJ Freedman, Nanopore Current Enhancements Lack Protein Charge Dependence and Elucidate Maximum Unfolding at Protein’s Isoelectric Point, Journal of the American Chemical Society 144 (7), 3063-3073. LS Lastra, YM Bandara, M Nguyen, N Farajpour, KJ Freedman, On the origins of conductive pulse sensing inside a nanopore, Nature Communications 13 (1), 1-11. LS Lastra, YMNDY Bandara, V Sharma, KJ Freedman, Protein and DNA Yield Current Enhancements, Slow Translocations, and an Enhanced Signal-to-Noise Ratio under a Salt Imbalance, ACS Sensors 7 (7), 1883-1893. YMNDY Bandara, KJ Freedman, Enhanced Signal to Noise Ratio Enables High Bandwidth Nanopore Recordings and Molecular Weight Profiling of Proteins, ACS Nano 16 (9), 14111-14120.

• WILLIAM GROVER

  PUBLICATIONS
  CandyCodes: simple universally unique edible identifiers for confirming the authenticity of pharmaceuticals

• JIA GUO

  GRANTS AWARDED	PUBLICATIONS	RECOGNITIONS AND ENGAGEMENTS
  "Ultra-fast blood flow imaging for functional brain mapping using velocity-selective arterial spin labeling” - National Institutes of Health, R01 Brain Initiative R01EB033210	J. Guo. Robust dual-module velocity-selective arterial spin labeling (dm-VSASL) with velocity-selective saturation and inversion. Magn Reson Med. 2022. doi: 10.1002/mrm.29513 L. Hernandez-Garcia, V. Aramendia, D. Bolar, MA. Fernandez-Seara, J. Guo, AJ. Madhuranthakam, H. Mutsaerts, J. Petr, Q. Qin, J. Schollenberger, Y. Suzuki, M. Taso, DL. Thomas, MJP. van Osch, Z. Wang, J. Woods, MY. Zhao, L. Yan, L. Zhao, TW. Okell. Recent technical developments in ASL: a review of the state of the art. Magn Reson Med. 2022;88(5):2021-42. doi: 10.1002/mrm.29381. Q. Qin, DC. Alsop, DS. Bolar, L, Hernandez-Garcia, J. Meakin, D. Liu, KS. Nayak, S. Schmid, MJP. Van Osch, EC. Wong, J. Woods, G. Zaharchuk, MY. Zhao, Z. Zun, J. Guo. Velocity Selective Arterial Spin Labeling Perfusion MRI: A Review of the State of the Art and Recommendations for Clinical Implementation. Magn Reson Med. 2022;88(4):1528-47. doi: 10.1002/mrm.29371. AP. Fan; G. Zaharchuk, O. Henriksen, H. An, D. Chen, J. Guo. Cerebral blood flow imaging in the era of PET/MRI and machine learning. JCBFM. 2022;42(1_suppl): 276-276. doi: 10.1177/0271678X221096358 R. Hussein, M. Zhao, D. Shin, J. Guo, K. Chen, R. Armindo, G. Davidzon, M. Moseley, G. Zaharchuk. Multi-task deep learning for cerebrovascular disease classification and MRI-to-PET translation. ICPR 2022. 625.	Faculty Development Award, Academic Senate, University of California, Riverside

• XIAOPING HU

  PUBLICATIONS

  RECOGNITIONS AND ENGAGEMENTS

  Langley J, Hussain S, Huddleston DE, Bennett IJ, and Hu X. Locus coeruleus and its projections impact on age-related cognitive decline. Brain Connect (2021). Langley J, Hussain S, Huddleston DE, and Hu X. Nigral diffusivity, but not free water, correlates with iron content in Parkinson’s disease. Brain Communications 3.4 (2021): fcab251. Reardon AM, Li K, and Hu X. Improving between-group effect size for multi-site functional connectivity data via site-wise de-meaning. Frontiers Comput Neurosci 111, 2021.

  Named Chair of the Publication Committee, International Society for Magnetic Resonance in Medicine Elected Fellow of AAAS

• ELENA KOKKONI

  VIEW LAB WEBSITE

• JIAYU LIAO

  GRANTS	PUBLICATIONS	PATENT APPLICATIONS
  NIAID/NIH. NCEA # 2018-085. SRF # 2018-085-014. Drug Dose-Range Finding Study for Efficacy. (PI: Jiayu Liao) NIAID/NIH. NCEA # 2018-085. SRF # 2018-085-015. Efficacy of Siponimod for treating influenza A/Viet/1203/2004 (H5N1) virus infection in BALB/c mice (RDB-In Vivo - Seasonal and Pandemic Influenza Therapeutics (PI:Jiayu Liao) NIAID/NIH. NCEA # 2018-085. SRF # 2018-085-016. Siponimod treatment on lung viral titers and cytokines on days 3 and 6 post-2009 (H1N1pdm) infection (RDB-In Vivo - Seasonal and Pandemic Influenza Therapeutics). (PI: Jiayu Liao) NIAID/NIH. NCEA # 2018-085. SRF # 2018-085-017. Siponimod Testing (OBRRTR-DMID COVID-19). (PI: Jiayu Liao)	Dang,R., Rodgers,R.J., Garcia-Sastre,A., and Liao,J. Human SUMOylation Pathway Is Critical for Influenza B Virus. Viruses 2022, 14, 34 Madahar,V., Rodgers,V.G.J.,  Liao,J. SUMOylation of SARS-CoV-2 Nucleocapsid protein enhances its interaction affinity and plays a critical role for its nuclear translocation. 2022. bioRxiv. June,1. https://doi.org/10.1101/2022.05.31.494262. Way,G., Xiong,Z., Zheng,S.,Liao,J. 2022. A Novel SUMOylation Site in the Influenza A Virus NS1 Protein Identified with a Highly Sensitive and Quantitative FRET Assay. International Journal of Biotechnology and Bioengineering, Volume 8 Issue 2, October 2022. 19-21. Liu,C., Dang,R., Liao,J. 2022. Dissecting Human and Influenza Virus Interaction with qFRET Technology. UCR Undergraduate Research Journal. 9-17	Jiayu Liao, Zhehao Xiong, George Way, Yang Song, Vipul Madahar, Runrui Dang, Hilda Wiryawan Chan. Sumoylation Inhibitors and Methods of Use Thereof. US Provisional Patent Application. No.63/406,154.

• HUINAN LIU

  View LAB WEBSITE 

• ROBERT MCKEE

  View Profile

• JOSHUA MORGAN

  PUBLICATIONS

  RECOGNITIONS AND ENGAGEMENTS

  Schwan J, Alva TR, Nava G, Rodriguez CB, Dunn Z, Chartron JW, Morgan JT, Wang P, Mangolini L. (2021) Efficient Facemask Decontamination via Forced Ozone Convection. Scientific Reports. In Press. Preprint: Schwan J, Alva TR, Nava G, Rodriguez CB, Dunn Z, Chartron JW,Morgan JT, Wang P, Mangolini L. (2021) Efficient Facemask Decontamination via Forced Ozone Convection. arXiv:2007.09280 Sanchez MM, Morgan JT (2021) Generation of self-assembled vascularized human skin equivalents. Journal of Visual Experiments. 168. PMID: 33645584 DOI: 10.3791/62125

  UC Riverside Academic Senate – 2022 Regents’ Faculty Development (7/2022-6/2024

• JIN NAM

  PUBLICATIONS

  K. Ma, X. Xiong, W. Li, J. Nam, M. Qu, S. Kay (2022) The actin cytoskeleton-MRTF/SRF cascade transduces cellular physical niche cues to entrain circadian clock. Journal of Cell Science 135(19): jcs260094. A. Banerjee, Y. Tai, N.V. Myung, J. Nam (2022) Non-destructive characterization of bone mineral content by machine learning-assisted electrochemical impedance spectroscopy. Frontiers in Bioengineering and Biotechnology 10:961108. S. Yu, Y. Tai, J. Milam-Guerrero, J. Nam, N.V. Myung (2022) Electrospun organic piezoelectric nanofibers and their energy and bio applications. Nano Energy 107174. S. Yu, J. Milam-Guerrero, Y. Tai, S. Yang, Y. Choi, J. Nam, and N.V. Myung (2021) Maximizing polyacrylonitrile nanofiber piezoelectric properties through optimization of electrospinning and post thermal treatment processes. ACS Applied Polymer Materials 4(1): 635-644. Y. Tai, A. Banerjee, R. Goodrich, L. Jin, and J. Nam (2021) Development and Utilization of Multifunctional Polymeric Scaffolds for the regulation of Physical Cellular Microenvironments. Polymers 13(22): 3880.

• IMAN NOSHADI

  GRANTS	PUBLICATIONS	PATENTS
  NSF-(2022-2023); In situ, handheld, 3D bioprinting of hydrogel sealant for corneal tissue repair and regeneration.; Role: PI NSF-APEX-(2022-2023); Development of Highly Adhesive Hydrogel for Cornea Tissue Regeneration; Role: PI	Azim, S. M., Sharma, A., Noshadi, I., Shatabda, S., & Dehzangi, I. (2022). A convolutional neural network-based tool for predicting protein AMPylation sites from binary profile representation. Scientific Reports, 12(1). Baghdasarian, S., Saleh, B., Baidya, A., Kim, H., Ghovvati, M., Sani, E. S., Haghniaz, R., Madhu, S., Kanelli, M., Noshadi, I., & Annabi, N. (2022). Engineering a naturally derived hemostatic sealant for sealing internal organs. Materials Today Bio, 13, 100199.  Kanjilal, B., Sharifi, N., Masoumi, A., & Noshadi, I. (2022). Bionanofluids and mass transfer characteristics. Nanofluids and Mass Transfer, 217–244	Iman Noshadi. Biocompatible oxygen gas generating devices for tissue engineering. US11389583B2

• GIULIA PALERMO

  PUBLICATIONS

  RECOGNITIONS AND ENGAGEMENTS

  Ł. Nierzwicki, K. W. East, J. Binz, R. V. Hsu, M. Ahsan, P. R. Arantes, E. Skeens, M. Pacesa, M. Jinek, G. P. Lisi* and G. Palermo.* Principles of Target DNA Cleavage and Role of Mg2+ in the Catalysis of CRISPR-Cas9. Nature Catalysis 2022, 5, 912–922. M. Pacesa, C-H. Lin, A. Cléry, A. Saha, P. R. Arantes, K. Bargsten, M. J. Irby, F. H.T. Allain, G. Palermo, P. Cameron, P. D. Donohoue and M. Jinek. Structural basis for Cas9 off-target activity. Cell 2022, 185, 4067–4081. M. Rossetti, R. Merlo, N. Bagheri, D. Moscone, A. Valenti, A. Saha, P.R. Arantes, R. Ippodrino, F. Ricci, I. Treglia, E. Delibato, J. van der Oost, G. Palermo,* G. Perugino* and A. Porchetta.* Enhancement of CRISPR/Cas12a trans-cleavage Activity Using Hairpin DNA Reporters. Nucleic Acids Res. 2022, gkac578. A. Saha, P. R. Arantes and G. Palermo.* Dynamics and Mechanism of CRISPR-Cas9 Visualized through Computational Methods. Curr. Opin. Struct. Biol. 2022, 75, 102400. J. Wang, E. Skeens, P. R. Arantes, F. Maschietto, B. Allen, G. Kyro, G. P. Lisi* and G. Palermo,* V. S. Batista.* Structural Basis for Reduced Dynamics of Three Engineered HNH Endonuclease Lys-to-Ala Mutants of the Clustered Regularly Interspaced Short Palindromic Repeat-Associated 9 Enzyme. Biochemistry 2022, 61, 785–794. P. R. Arantes, A. C. Patel and G. Palermo.* Emerging Methods and Applications to Decrypt Allostery in Proteins and Nucleic Acids. J. Mol. Biol. 2022, 167518. H. B. Belato, A. M. D’Ordine, L. Nierzwicki, G. Jogl, G. Palermo* and G. P. Lisi.* Structural and Dynamic Insights into the HNH Nuclease of Divergent Cas9 Species. J. Struct. Biol. 2022, 214, 107814.

  2022/10 - DOE-NERSC Innovative Use of High-Performance Computing Award 2022/05 - Outstanding Doctoral Dissertation Advisor/Mentoring Award, UCR 2022/03 - ACS OpenEye Outstanding Junior Faculty Award in Computational Chemistry 2022/01 - NSF CAREER Award

• HYLE PARK

  View PROFILE

• VICTOR G.J. RODGERS

  GRANTS AWARDED	PUBLICATIONS	RECOGNITIONS AND ENGAGEMENTS
  “Bridges to the Baccalaureate Research Training Program at University of California, Riverside (PI: Rodgers V, transferred from B. Ford) - National Institutes of Health, $1,437,280 Development of a fieldable direct osmotherapy device for the point-of-injury reduction of cerebral edema following penetrating traumatic brain injury - Department of Defense, UCR subaward $711,428 Device to Treat Acute Edema in Spinal Cord Injury - UCR Proof of Concept Program $50,000  LEARN MORE	Terry TL, Givens BE, Adamcakova-Dodd A, Thorne PS, Rodgers VGJ, Salem AK (2021) Encapsulating polyethyleneimine-DNA nanoplexes into PEGylated biodegradable microparticles increases transgene expression in vitro and reduces inflammatory responses in vivo. AAPS PharmSciTech, 2021 Feb 9;22(2):69. doi: 10.1208/s12249-021-01932-z. Hale CS, Yonan JM, Batarseh R, Chaar R, Jonak CR, Binder DK, Rodgers VGJ (2020) Implantable Osmotic Transport Device Can Reduce Edema After Severe Contusion Spinal Cord Injury, Frontiers in Bioengineering and Biotechnology: Biomechanics, Vol. 8, Page 806, DOI https://doi.org/10.3389/fbioe.2020.00806. Erudaitius DT, Buettner GR, Rodgers VGJ (2020) The latency of peroxisomal catalase in terms of effectiveness factor for pancreatic and glioblastoma cancer cell lines in the presence of high concentrations of H2O2: Implications for the use of pharmacological ascorbate in cancer therapy, Free Radical Biology and Medicine, Volume 156,Pages 20-25, ISSN 0891-5849,https://doi.org/10.1016/j.freeradbiomed.2020.05.023.	Associate Editor, Frontiers in Bioengineering and Biotechnology, Biomechanics (2022 - ) Advisory Board, Department of Biomedical Engineering, Washington University in St. Louis (2015 - )  Reviewer, Ford Foundation Science Panel on Engineering (2014-2018, 2021) Charter Member, NIH Study Section Biomaterials and Biointerfaces (2015-2021)

• VALENTINE VULLEV

  View Lab Website

FACULTY DIRECTORY

• CORE FACULTY

• COOPERATING FACULTY